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Polo-like kinase 1 inhibits DNA damage response during mitosis
In response to genotoxic stress, cells protect their genome integrity by activation of a conserved DNA damage response (DDR) pathway that coordinates DNA repair and progression through the cell cycle. Extensive modification of the chromatin flanking the DNA lesion by ATM kinase and RNF8/RNF168 ubiqu...
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| 出版年: | Cell Cycle |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4613155/ https://ncbi.nlm.nih.gov/pubmed/25607646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.977067 |
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