Targeting the Checkpoint to Kill Cancer Cells

Por Benada, Jan, Macurek, Libor
Publicado no Biomolecules (2015)

Polo-like kinase 1 inhibits DNA damage response during mitosis

Por Benada, Jan, Burdová, Kamila, Lidak, Tomáš, von Morgen, Patrick, Macurek, Libor
Publicado no Cell Cycle (2015)

Inhibition of WIP1 phosphatase sensitizes breast cancer cells to genotoxic stress and to MDM2 antagonist nutlin-3

Por Pechackova, Sona, Burdova, Kamila, Benada, Jan, Kleiblova, Petra, Jenikova, Gabriela, Macurek, Libor
Publicado no Oncotarget (2016)

Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis

Por Macurek, Libor, Benada, Jan, Müllers, Erik, Halim, Vincentius A., Krejčíková, Kateřina, Burdová, Kamila, Pecháčková, Sona, Hodný, Zdeněk, Lindqvist, Arne, Medema, René H., Bartek, Jiri
Publicado em 2013

Gain-of-function mutations of PPM1D/Wip1 impair the p53-dependent G1 checkpoint

Por Kleiblova, Petra, Shaltiel, Indra A., Benada, Jan, Ševčík, Jan, Pecháčková, Soňa, Pohlreich, Petr, Voest, Emile E., Dundr, Pavel, Bartek, Jiri, Kleibl, Zdenek, Medema, René H., Macurek, Libor
Publicado em 2013