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Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis
Cells are constantly challenged by DNA damage and protect their genome integrity by activation of an evolutionary conserved DNA damage response pathway (DDR). A central core of DDR is composed of a spatiotemporally ordered net of post-translational modifications, among which protein phosphorylation...
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主要な著者: | , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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Landes Bioscience
2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3575454/ https://ncbi.nlm.nih.gov/pubmed/23255129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23057 |
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