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Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis

Cells are constantly challenged by DNA damage and protect their genome integrity by activation of an evolutionary conserved DNA damage response pathway (DDR). A central core of DDR is composed of a spatiotemporally ordered net of post-translational modifications, among which protein phosphorylation...

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書誌詳細
主要な著者: Macurek, Libor, Benada, Jan, Müllers, Erik, Halim, Vincentius A., Krejčíková, Kateřina, Burdová, Kamila, Pecháčková, Sona, Hodný, Zdeněk, Lindqvist, Arne, Medema, René H., Bartek, Jiri
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575454/
https://ncbi.nlm.nih.gov/pubmed/23255129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23057
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