Učitavanje...
Residual Cdk1/2 activity after DNA damage promotes senescence
In response to DNA damage, a cell can be forced to permanently exit the cell cycle and become senescent. Senescence provides an early barrier against tumor development by preventing proliferation of cells with damaged DNA. By studying single cells, we show that Cdk activity persists after DNA damage...
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| Izdano u: | Aging Cell |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
John Wiley and Sons Inc.
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418196/ https://ncbi.nlm.nih.gov/pubmed/28345297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12588 |
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