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VPS54 and the wobbler mouse
The wobbler mouse is an animal model for human motor neuron disease, such as amyotrophic lateral sclerosis (ALS). The spontaneous, recessive wobbler mutation causes degeneration of upper and lower motor neurons leading to progressive muscle weakness with striking similarities to the ALS pathology. T...
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| Published in: | Front Neurosci |
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| Main Author: | |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Frontiers Media S.A.
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612502/ https://ncbi.nlm.nih.gov/pubmed/26539077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00381 |
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