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Inflammation and neuronal death in the motor cortex of the wobbler mouse, an ALS animal model

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder of the upper and lower motor neurons, characterized by rapid progressive weakness, muscle atrophy, dysarthria, dysphagia, and dyspnea. Whereas the exact cause of ALS remains uncertain, the wobbler mouse (phenotype...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Dahlke, Carolin, Saberi, Darius, Ott, Bastian, Brand-Saberi, Beate, Schmitt-John, Thomas, Theiss, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657283/
https://ncbi.nlm.nih.gov/pubmed/26597538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0435-0
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