Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex

The multisubunit Golgi-associated retrograde protein (GARP) complex is required for tethering and fusion of endosome-derived transport vesicles to the trans-Golgi network. Mutation of leucine-967 to glutamine in the Vps54 subunit of GARP is responsible for spinal muscular atrophy in the wobbler mous...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pérez-Victoria, F. Javier, Abascal-Palacios, Guillermo, Tascón, Igor, Kajava, Andrey, Magadán, Javier G., Pioro, Erik P., Bonifacino, Juan S., Hierro, Aitor
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919957/
https://ncbi.nlm.nih.gov/pubmed/20615984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004756107
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge