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VPS54 and the wobbler mouse
The wobbler mouse is an animal model for human motor neuron disease, such as amyotrophic lateral sclerosis (ALS). The spontaneous, recessive wobbler mutation causes degeneration of upper and lower motor neurons leading to progressive muscle weakness with striking similarities to the ALS pathology. T...
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| Publicado no: | Front Neurosci |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4612502/ https://ncbi.nlm.nih.gov/pubmed/26539077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00381 |
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