Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging

Acute aerobic exercise increases reactive oxygen species and could potentially damage proteins, but exercise training (ET) enhances mitochondrial respiration irrespective of age. Here, we report a differential impact of ET on protein quality in young and older participants. Using mass spectrometry w...

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Bibliografske podrobnosti
izdano v:J Gerontol A Biol Sci Med Sci
Main Authors: Johnson, Matthew L., Irving, Brian A., Lanza, Ian R., Vendelbo, Mikkel H., Konopka, Adam R., Robinson, Matthew M., Henderson, Gregory C., Klaus, Katherine A., Morse, Dawn M., Heppelmann, Carrie, Bergen, H. Robert, Dasari, Surendra, Schimke, Jill M., Jakaitis, Daniel R., Nair, K. Sreekumaran
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612384/
https://ncbi.nlm.nih.gov/pubmed/25504576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu221
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