Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging

Acute aerobic exercise increases reactive oxygen species and could potentially damage proteins, but exercise training (ET) enhances mitochondrial respiration irrespective of age. Here, we report a differential impact of ET on protein quality in young and older participants. Using mass spectrometry w...

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書目詳細資料
發表在:J Gerontol A Biol Sci Med Sci
Main Authors: Johnson, Matthew L., Irving, Brian A., Lanza, Ian R., Vendelbo, Mikkel H., Konopka, Adam R., Robinson, Matthew M., Henderson, Gregory C., Klaus, Katherine A., Morse, Dawn M., Heppelmann, Carrie, Bergen, H. Robert, Dasari, Surendra, Schimke, Jill M., Jakaitis, Daniel R., Nair, K. Sreekumaran
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612384/
https://ncbi.nlm.nih.gov/pubmed/25504576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu221
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