Differential Effect of Endurance Training on Mitochondrial Protein Damage, Degradation, and Acetylation in the Context of Aging

Acute aerobic exercise increases reactive oxygen species and could potentially damage proteins, but exercise training (ET) enhances mitochondrial respiration irrespective of age. Here, we report a differential impact of ET on protein quality in young and older participants. Using mass spectrometry w...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Johnson, Matthew L., Irving, Brian A., Lanza, Ian R., Vendelbo, Mikkel H., Konopka, Adam R., Robinson, Matthew M., Henderson, Gregory C., Klaus, Katherine A., Morse, Dawn M., Heppelmann, Carrie, Bergen, H. Robert, Dasari, Surendra, Schimke, Jill M., Jakaitis, Daniel R., Nair, K. Sreekumaran
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4612384/
https://ncbi.nlm.nih.gov/pubmed/25504576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/glu221
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