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Release of skeletal muscle peptide fragments identifies individual proteins degraded during insulin deprivation in type 1 diabetic humans and mice

Insulin regulates skeletal muscle protein degradation, but the types of proteins being degraded in vivo remain to be determined due to methodological limitations. We present a method to assess the types of skeletal muscle proteins that are degraded by extracting their degradation products as low-mol...

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Dettagli Bibliografici
Pubblicato in:Am J Physiol Endocrinol Metab
Autori principali: Robinson, Matthew M., Dasari, Surendra, Karakelides, Helen, Bergen, H. Robert, Nair, K. Sreekumaran
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142007/
https://ncbi.nlm.nih.gov/pubmed/27436610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00175.2016
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