Kisspeptin Receptor Haplo-insufficiency Causes Premature Ovarian Failure Despite Preserved Gonadotropin Secretion

Premature ovarian failure (POF) affects 1% of women in reproductive age, but its etiology remains uncertain. Whereas kisspeptins, the products of Kiss1 that act via Kiss1r (aka, Gpr54), are known to operate at the hypothalamus to control GnRH/gonadotropin secretion, additional actions at other repro...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Endocrinology
Egile Nagusiak: Gaytan, Francisco, Garcia-Galiano, David, Dorfman, Mauricio D., Manfredi-Lozano, Maria, Castellano, Juan M., Dissen, Gregory A., Ojeda, Sergio R., Tena-Sempere, Manuel
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Endocrine Society 2014
Gaiak:
Reproduction-Development
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611053/
https://ncbi.nlm.nih.gov/pubmed/24885574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1110
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