Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity

Kisspeptins, ligands of the receptor, Gpr54, are potent stimulators of puberty and fertility. Yet, whether direct kisspeptin actions on GnRH neurons are sufficient for the whole repertoire of their reproductive effects remains debatable. To dissect out direct vs. indirect effects of kisspeptins on G...

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Publicado no:Sci Rep
Main Authors: León, Silvia, Barroso, Alexia, Vázquez, María J., García-Galiano, David, Manfredi-Lozano, María, Ruiz-Pino, Francisco, Heras, Violeta, Romero-Ruiz, Antonio, Roa, Juan, Schutz, Günther, Kirilov, Milen, Gaytan, Francisco, Pinilla, Leonor, Tena-Sempere, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709743/
https://ncbi.nlm.nih.gov/pubmed/26755241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19206
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