Direct Actions of Kisspeptins on GnRH Neurons Permit Attainment of Fertility but are Insufficient to Fully Preserve Gonadotropic Axis Activity

Kisspeptins, ligands of the receptor, Gpr54, are potent stimulators of puberty and fertility. Yet, whether direct kisspeptin actions on GnRH neurons are sufficient for the whole repertoire of their reproductive effects remains debatable. To dissect out direct vs. indirect effects of kisspeptins on G...

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發表在:Sci Rep
Main Authors: León, Silvia, Barroso, Alexia, Vázquez, María J., García-Galiano, David, Manfredi-Lozano, María, Ruiz-Pino, Francisco, Heras, Violeta, Romero-Ruiz, Antonio, Roa, Juan, Schutz, Günther, Kirilov, Milen, Gaytan, Francisco, Pinilla, Leonor, Tena-Sempere, Manuel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4709743/
https://ncbi.nlm.nih.gov/pubmed/26755241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19206
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