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Loss of Ntrk2/Kiss1r Signaling in Oocytes Causes Premature Ovarian Failure

Neurotrophins (NTs), once believed to be neural-specific trophic factors, are now known to also provide developmental cues to non-neural cells. In the ovary, NTs contribute to both the formation and development of follicles. Here we show that oocyte-specific deletion of the Ntrk2 gene that encodes t...

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Detalhes bibliográficos
Main Authors: Dorfman, Mauricio D., Garcia-Rudaz, Cecilia, Alderman, Zefora, Kerr, Bredford, Lomniczi, Alejandro, Dissen, Gregory A., Castellano, Juan Manuel, Garcia-Galiano, David, Gaytan, Francisco, Xu, Baoji, Tena-Sempere, Manuel, Ojeda, Sergio R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4097998/
https://ncbi.nlm.nih.gov/pubmed/24877631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1111
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