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Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin

Terreic acid is a metabolite with antibiotic properties produced by the fungus Aspergillus terreus, but its cellular target remains unknown. We recently reported that terreic acid inactivates the bacterial cell wall biosynthetic enzyme MurA in vitro by covalent reaction with residue Cys115 in a simi...

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Veröffentlicht in:J Basic Microbiol
Hauptverfasser: Olesen, Sanne H., Ingles, Donna J., Yang, Yan, Schönbrunn, Ernst
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610358/
https://ncbi.nlm.nih.gov/pubmed/23686727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jobm.201200617
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