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Differential antibacterial properties of the MurA inhibitors terreic acid and fosfomycin

Terreic acid is a metabolite with antibiotic properties produced by the fungus Aspergillus terreus, but its cellular target remains unknown. We recently reported that terreic acid inactivates the bacterial cell wall biosynthetic enzyme MurA in vitro by covalent reaction with residue Cys115 in a simi...

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Bibliographic Details
Published in:J Basic Microbiol
Main Authors: Olesen, Sanne H., Ingles, Donna J., Yang, Yan, Schönbrunn, Ernst
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610358/
https://ncbi.nlm.nih.gov/pubmed/23686727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jobm.201200617
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