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Autoregulated paracellular clearance of amyloid-β across the blood-brain barrier

The blood-brain barrier (BBB) is essential for maintaining brain homeostasis and protecting neural tissue from damaging blood-borne agents. The barrier is characterized by endothelial tight junctions that limit passive paracellular diffusion of polar solutes and macromolecules from blood to brain. D...

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Bibliografische gegevens
Gepubliceerd in:Sci Adv
Hoofdauteurs: Keaney, James, Walsh, Dominic M., O’Malley, Tiernan, Hudson, Natalie, Crosbie, Darragh E., Loftus, Teresa, Sheehan, Florike, McDaid, Jacqueline, Humphries, Marian M., Callanan, John J., Brett, Francesca M., Farrell, Michael A., Humphries, Peter, Campbell, Matthew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Association for the Advancement of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610013/
https://ncbi.nlm.nih.gov/pubmed/26491725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.1500472
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