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High-mobility group box 1 inhibits HCO(3)(−) absorption in medullary thick ascending limb through a basolateral receptor for advanced glycation end products pathway

High-mobility group box 1 (HMGB1) is a damage-associated molecule implicated in mediating kidney dysfunction in sepsis and sterile inflammatory disorders. HMGB1 is a nuclear protein released extracellularly in response to infection or injury, where it interacts with Toll-like receptor 4 (TLR4) and o...

詳細記述

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書誌詳細
出版年:Am J Physiol Renal Physiol
主要な著者: Good, David W., George, Thampi, Watts, Bruns A.
フォーマット: Artigo
言語:Inglês
出版事項: American Physiological Society 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609918/
https://ncbi.nlm.nih.gov/pubmed/26180239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00227.2015
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