Basolateral LPS inhibits NHE3 and HCO(3)(−) absorption through TLR4/MyD88-dependent ERK activation in medullary thick ascending limb

Sepsis is associated with defects in renal tubule function, but the underlying mechanisms are incompletely understood. Recently, we demonstrated that Gram-negative bacterial lipopolysaccharide (LPS) inhibits HCO(3)(−) absorption in the medullary thick ascending limb (MTAL) through activation of Toll...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Watts, Bruns A., George, Thampi, Sherwood, Edward R., Good, David W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2011
Materias:
Membrane Transporters, Ion Channels and Pumps
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233797/
https://ncbi.nlm.nih.gov/pubmed/21881005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00237.2011
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares