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High sodium intake increases HCO(3)(−) absorption in medullary thick ascending limb through adaptations in basolateral and apical Na(+)/H(+) exchangers
A high sodium intake increases the capacity of the medullary thick ascending limb (MTAL) to absorb HCO(3)(−). Here, we examined the role of the apical NHE3 and basolateral NHE1 Na(+)/H(+) exchangers in this adaptation. MTALs from rats drinking H(2)O or 0.28 M NaCl for 5–7 days were perfused in vitro...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154595/ https://ncbi.nlm.nih.gov/pubmed/21613418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00106.2011 |
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