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High sodium intake increases HCO(3)(−) absorption in medullary thick ascending limb through adaptations in basolateral and apical Na(+)/H(+) exchangers

A high sodium intake increases the capacity of the medullary thick ascending limb (MTAL) to absorb HCO(3)(−). Here, we examined the role of the apical NHE3 and basolateral NHE1 Na(+)/H(+) exchangers in this adaptation. MTALs from rats drinking H(2)O or 0.28 M NaCl for 5–7 days were perfused in vitro...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Good, David W., George, Thampi, Watts, Bruns A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154595/
https://ncbi.nlm.nih.gov/pubmed/21613418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00106.2011
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