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High-mobility group box 1 inhibits HCO(3)(−) absorption in medullary thick ascending limb through a basolateral receptor for advanced glycation end products pathway
High-mobility group box 1 (HMGB1) is a damage-associated molecule implicated in mediating kidney dysfunction in sepsis and sterile inflammatory disorders. HMGB1 is a nuclear protein released extracellularly in response to infection or injury, where it interacts with Toll-like receptor 4 (TLR4) and o...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609918/ https://ncbi.nlm.nih.gov/pubmed/26180239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00227.2015 |
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