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PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation

Transcription elongation programs are vital for the precise regulation of several biological processes. One key regulator of such programs is the P-TEFb kinase, which phosphorylates RNA polymerase II (Pol II) once released from the inhibitory 7SK small nuclear ribonucleoprotein (snRNP) complex. Alth...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Gudipaty, Swapna Aravind, McNamara, Ryan P., Morton, Emily L., D'Orso, Iván
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609742/
https://ncbi.nlm.nih.gov/pubmed/26324325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00226-15
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