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PPM1G Binds 7SK RNA and Hexim1 To Block P-TEFb Assembly into the 7SK snRNP and Sustain Transcription Elongation

Transcription elongation programs are vital for the precise regulation of several biological processes. One key regulator of such programs is the P-TEFb kinase, which phosphorylates RNA polymerase II (Pol II) once released from the inhibitory 7SK small nuclear ribonucleoprotein (snRNP) complex. Alth...

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Bibliografiset tiedot
Julkaisussa:Mol Cell Biol
Päätekijät: Gudipaty, Swapna Aravind, McNamara, Ryan P., Morton, Emily L., D'Orso, Iván
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609742/
https://ncbi.nlm.nih.gov/pubmed/26324325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00226-15
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