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KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II

The transition from transcription initiation to elongation at promoters of primary response genes (PRGs) in metazoan cells is controlled by inducible transcription factors, which utilize P-TEFb to phosphorylate RNA polymerase II (Pol II) in response to stimuli. Prior to stimulation, a fraction of P-...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: McNamara, Ryan P., Reeder, Jonathan E., McMillan, Elizabeth A., Bacon, Curtis W., McCann, Jennifer L., D’Orso, Iván
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714561/
https://ncbi.nlm.nih.gov/pubmed/26725010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.11.004
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