Targeting the miR-221-222/PUMA/BAK/BAX pathway abrogates dexamethasone resistance in multiple myeloma

Despite recent therapeutic advances that have doubled the median survival time of patients with multiple myeloma (MM), intratumor genetic heterogeneity contributes to disease progression and emergence of drug resistance. MicroRNAs (miRs), are noncoding small RNAs that play important roles in the reg...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cancer Res
Päätekijät: Zhao, Jian-Jun, Chu, Zhang-Bo, Hu, Yu, Lin, Jianhong, Wang, Zhongqiu, Jiang, Meng, Chen, Ming, Wang, Xujun, Kang, Yue, Zhou, Yangsheng, Ni Chonghaile, Triona, Johncilla, Melanie E., Tai, Yu-Tzu, Cheng, Jin Q., Letai, Antony, Munshi, Nikhil C., Anderson, Kenneth C., Carrasco, Ruben D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609291/
https://ncbi.nlm.nih.gov/pubmed/26249174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0457
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