MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

BACKGROUND: MiR-221 and miR-222 (miR-221/222) are frequently up-regulated in various types of human malignancy including glioblastoma. Recent studies have reported that miR-221/222 regulate cell growth and cell cycle progression by targeting p27 and p57. However the underlying mechanism involved in...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Chun-Zhi, Zhang, Jun-Xia, Zhang, An-Ling, Shi, Zhen-Dong, Han, Lei, Jia, Zhi-Fan, Yang, Wei-Dong, Wang, Guang-Xiu, Jiang, Tao, You, Yong-Ping, Pu, Pei-Yu, Cheng, Jin-Quan, Kang, Chun-Sheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2939570/
https://ncbi.nlm.nih.gov/pubmed/20813046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-229
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