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Knockout of miR-221 and miR-222 reveals common and specific targets for paralogous miRNAs

MicroRNAs (miRNAs) regulate the expression of mRNA through sequence-specific binding of the 3′ untranslated region (UTR). The seed sequence of miRNAs is the key determinant for target site recognition. Paralogous miRNAs, which share the same seed sequences but differ in their 3′ regions, are known t...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:RNA Biol
Main Authors: Jeong, Geon, Lim, Yeong-Hwan, Kim, Nam Joong, Wee, Gabbine, Kim, Young-Kook
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5324760/
https://ncbi.nlm.nih.gov/pubmed/27981894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2016.1269994
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