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Improving RNA-Seq expression estimation by modeling isoform- and exon-specific read sequencing rate
BACKGROUND: The high-throughput sequencing technology, RNA-Seq, has been widely used to quantify gene and isoform expression in the study of transcriptome in recent years. Accurate expression measurement from the millions or billions of short generated reads is obstructed by difficulties. One is amb...
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| 出版年: | BMC Bioinformatics |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4609108/ https://ncbi.nlm.nih.gov/pubmed/26475308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0750-6 |
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