Improving RNA-Seq expression estimation by modeling isoform- and exon-specific read sequencing rate

BACKGROUND: The high-throughput sequencing technology, RNA-Seq, has been widely used to quantify gene and isoform expression in the study of transcriptome in recent years. Accurate expression measurement from the millions or billions of short generated reads is obstructed by difficulties. One is amb...

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Bibliografiske detaljer
Udgivet i:BMC Bioinformatics
Main Authors: Liu, Xuejun, Shi, Xinxin, Chen, Chunlin, Zhang, Li
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Methodology Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609108/
https://ncbi.nlm.nih.gov/pubmed/26475308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0750-6
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