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Improving RNA-Seq expression estimation by modeling isoform- and exon-specific read sequencing rate

BACKGROUND: The high-throughput sequencing technology, RNA-Seq, has been widely used to quantify gene and isoform expression in the study of transcriptome in recent years. Accurate expression measurement from the millions or billions of short generated reads is obstructed by difficulties. One is amb...

詳細記述

保存先:
書誌詳細
出版年:BMC Bioinformatics
主要な著者: Liu, Xuejun, Shi, Xinxin, Chen, Chunlin, Zhang, Li
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4609108/
https://ncbi.nlm.nih.gov/pubmed/26475308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0750-6
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