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Haplotype and isoform specific expression estimation using multi-mapping RNA-seq reads
We present a novel pipeline and methodology for simultaneously estimating isoform expression and allelic imbalance in diploid organisms using RNA-seq data. We achieve this by modeling the expression of haplotype-specific isoforms. If unknown, the two parental isoform sequences can be individually re...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188795/ https://ncbi.nlm.nih.gov/pubmed/21310039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-2-r13 |
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