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sCNAphase: using haplotype resolved read depth to genotype somatic copy number alterations from low cellularity aneuploid tumors

Accurate identification of copy number alterations is an essential step in understanding the events driving tumor progression. While a variety of algorithms have been developed to use high-throughput sequencing data to profile copy number changes, no tool is able to reliably characterize ploidy and...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Chen, Wenhan, Robertson, Alan J., Ganesamoorthy, Devika, Coin, Lachlan J.M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389684/
https://ncbi.nlm.nih.gov/pubmed/27903916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1086
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