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sCNAphase: using haplotype resolved read depth to genotype somatic copy number alterations from low cellularity aneuploid tumors

Accurate identification of copy number alterations is an essential step in understanding the events driving tumor progression. While a variety of algorithms have been developed to use high-throughput sequencing data to profile copy number changes, no tool is able to reliably characterize ploidy and...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Chen, Wenhan, Robertson, Alan J., Ganesamoorthy, Devika, Coin, Lachlan J.M.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389684/
https://ncbi.nlm.nih.gov/pubmed/27903916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1086
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