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GROM-RD: resolving genomic biases to improve read depth detection of copy number variants
Amplifications or deletions of genome segments, known as copy number variants (CNVs), have been associated with many diseases. Read depth analysis of next-generation sequencing (NGS) is an essential method of detecting CNVs. However, genome read coverage is frequently distorted by various biases of...
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| Udgivet i: | PeerJ |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
PeerJ Inc.
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4369336/ https://ncbi.nlm.nih.gov/pubmed/25802807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.836 |
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