Carregant...
Akt kinase-mediated checkpoint of cGAS DNA sensing pathway
Upon DNA stimulation, cyclic GMP-AMP synthetase (cGAS) synthesizes the second messenger cyclic GMP-AMP (cGAMP) that binds to the STING, triggering antiviral interferon-β (IFN-β) production. However, it has remained undetermined how hosts regulate cGAS enzymatic activity after the resolution of DNA i...
Guardat en:
| Publicat a: | Cell Rep |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607670/ https://ncbi.nlm.nih.gov/pubmed/26440888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.09.007 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|