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Many Private Mutations Originate From The First Few Divisions Of A Human Colorectal Adenoma
Intratumoral mutational heterogeneity (ITH) or the presence of different private mutations in different parts of the same tumor is commonly observed in human tumors. The mechanisms generating such ITH are uncertain. Here we find ITH can be remarkably well-structured by measuring point mutations, chr...
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| Izdano u: | J Pathol |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607608/ https://ncbi.nlm.nih.gov/pubmed/26119426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4581 |
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