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A Big Bang model of human colorectal tumor growth
What happens in the early, still undetectable human malignancy is unknown because direct observations are impractical. Here we present and validate a “Big Bang” model, whereby tumors grow predominantly as a single expansion producing numerous intermixed sub-clones that are not subject to stringent s...
में बचाया:
| में प्रकाशित: | Nat Genet |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4575589/ https://ncbi.nlm.nih.gov/pubmed/25665006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3214 |
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