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Early mutation bursts in colorectal tumors

Tumor growth is an evolutionary process involving accumulation of mutations, copy number alterations, and cancer stem cell (CSC) division and differentiation. As direct observation of this process is impossible, inference regarding when mutations occur and how stem cells divide is difficult. However...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhao, Junsong, Salomon, Matthew P., Shibata, Darryl, Curtis, Christina, Siegmund, Kimberly, Marjoram, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336211/
https://ncbi.nlm.nih.gov/pubmed/28257429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172516
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