Early mutation bursts in colorectal tumors

Tumor growth is an evolutionary process involving accumulation of mutations, copy number alterations, and cancer stem cell (CSC) division and differentiation. As direct observation of this process is impossible, inference regarding when mutations occur and how stem cells divide is difficult. However...

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Udgivet i:PLoS One
Main Authors: Zhao, Junsong, Salomon, Matthew P., Shibata, Darryl, Curtis, Christina, Siegmund, Kimberly, Marjoram, Paul
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5336211/
https://ncbi.nlm.nih.gov/pubmed/28257429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172516
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