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The Effector Domain of MARCKS Is a Nuclear Localization Signal that Regulates Cellular PIP2 Levels and Nuclear PIP2 Localization

Translocation to the nucleus of diacylglycerol kinase (DGK)– ζ is dependent on a sequence homologous to the effector domain of Myristoylated Alanine Rich C-Kinase Substrate (MARCKS). These data would suggest that MARCKS could also localize to the nucleus. A single report demonstrated immunofluoresce...

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Foilsithe in:PLoS One
Main Authors: Rohrbach, Timothy D., Shah, Nishi, Jackson, William P., Feeney, Erin V., Scanlon, Samantha, Gish, Robert, Khodadadi, Ryan, Hyde, Stephen O., Hicks, Patricia H., Anderson, Joshua C., Jarboe, John S., Willey, Christopher D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607481/
https://ncbi.nlm.nih.gov/pubmed/26470026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140870
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