MARCKS mediates vascular contractility through regulating interactions between voltage-gated Ca(2+) channels and PIP(2)

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) acts as substrate and unmodified ligand for Gq-protein-coupled receptor signalling in vascular smooth muscle cells (VSMCs) that is central for initiating contractility. The present work investigated how PIP(2) might perform these two potentially conflic...

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Detalhes bibliográficos
Publicado no:Vascul Pharmacol
Main Authors: Jahan, Kazi S., Shi, Jian, Greenberg, Harry Z.E., Khavandi, Sam, Baudel, Miguel Martín-Aragón, Barrese, Vincenzo, Greenwood, Iain A., Albert, Anthony P.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549404/
https://ncbi.nlm.nih.gov/pubmed/32707323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vph.2020.106776
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