MARCKS phosphorylation is modulated by a peptide mimetic of MARCKS effector domain leading to increased radiation sensitivity in lung cancer cell lines

Lung cancer is the leading cause of cancer-associated mortality in the United States. Kinase hyperactivation is a known mechanism of tumorigenesis. The phosphorylation status of the plasma membrane-associated protein myristoylated alanine rich C-kinase substrate (MARCKS) effector domain (ED) was pre...

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Vydáno v:Oncol Lett
Hlavní autoři: Rohrbach, Timothy D., Jones, Robert B., Hicks, Patricia H., Weaver, Alice N., Cooper, Tiffiny S., Eustace, Nicholas J., Yang, Eddy S., Jarboe, John S., Anderson, Joshua C., Willey, Christopher D.
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403188/
https://ncbi.nlm.nih.gov/pubmed/28454237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.5550
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