A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma

Glioblastoma (GBM) is an aggressive malignancy with limited effectiveness of standard of care therapies including surgery, radiation, and temozolomide chemotherapy necessitating novel therapeutics. Unfortunately, GBMs also harbor several signaling alterations that protect them from traditional thera...

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Publicat a:Oncogene
Autors principals: Eustace, Nicholas J., Anderson, Joshua C., Warram, Jason M., Widden, Hayley N., Pedersen, Rune T., Alrefai, Hasan, Patel, Zeel, Hicks, Patricia H., Placzek, William J., Gillespie, G. Yancey, Hjelmeland, Anita B., Willey, Christopher D.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885995/
https://ncbi.nlm.nih.gov/pubmed/33077834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01511-9
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