A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma

Glioblastoma (GBM) is an aggressive malignancy with limited effectiveness of standard of care therapies including surgery, radiation, and temozolomide chemotherapy necessitating novel therapeutics. Unfortunately, GBMs also harbor several signaling alterations that protect them from traditional thera...

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Vydáno v:Oncogene
Hlavní autoři: Eustace, Nicholas J., Anderson, Joshua C., Warram, Jason M., Widden, Hayley N., Pedersen, Rune T., Alrefai, Hasan, Patel, Zeel, Hicks, Patricia H., Placzek, William J., Gillespie, G. Yancey, Hjelmeland, Anita B., Willey, Christopher D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885995/
https://ncbi.nlm.nih.gov/pubmed/33077834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01511-9
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