A cell-penetrating MARCKS mimetic selectively triggers cytolytic death in glioblastoma

Glioblastoma (GBM) is an aggressive malignancy with limited effectiveness of standard of care therapies including surgery, radiation, and temozolomide chemotherapy necessitating novel therapeutics. Unfortunately, GBMs also harbor several signaling alterations that protect them from traditional thera...

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Udgivet i:Oncogene
Main Authors: Eustace, Nicholas J., Anderson, Joshua C., Warram, Jason M., Widden, Hayley N., Pedersen, Rune T., Alrefai, Hasan, Patel, Zeel, Hicks, Patricia H., Placzek, William J., Gillespie, G. Yancey, Hjelmeland, Anita B., Willey, Christopher D.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7885995/
https://ncbi.nlm.nih.gov/pubmed/33077834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-020-01511-9
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