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MARCKS Regulates Growth, Radiation Sensitivity and is a Novel Prognostic Factor for Glioma

PURPOSE: This study assessed whether Myristoylated Alanine Rich C-Kinase Substrate (MARCKS) can regulate glioblastoma (GBM) growth, radiation sensitivity and clinical outcome. EXPERIMENTAL DESIGN: MARCKS protein levels were analyzed in five GBM explant cell lines and eight patient-derived xenograft...

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Detalhes bibliográficos
Main Authors: Jarboe, John S., Anderson, Joshua C., Duarte, Christine W., Mehta, Tapan, Nowsheen, Somaira, Hicks, Patricia H., Whitley, Alexander C., Rohrbach, Timothy D., McCubrey, Raymond O., Chiu, Sherard, Burleson, Tamara M., Bonner, James A., Gillespie, G. Yancey, Yang, Eddy S., Willey, Christopher D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756473/
https://ncbi.nlm.nih.gov/pubmed/22619307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3091
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