MARCKS Regulates Growth, Radiation Sensitivity and is a Novel Prognostic Factor for Glioma

PURPOSE: This study assessed whether Myristoylated Alanine Rich C-Kinase Substrate (MARCKS) can regulate glioblastoma (GBM) growth, radiation sensitivity and clinical outcome. EXPERIMENTAL DESIGN: MARCKS protein levels were analyzed in five GBM explant cell lines and eight patient-derived xenograft...

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Autori principali: Jarboe, John S., Anderson, Joshua C., Duarte, Christine W., Mehta, Tapan, Nowsheen, Somaira, Hicks, Patricia H., Whitley, Alexander C., Rohrbach, Timothy D., McCubrey, Raymond O., Chiu, Sherard, Burleson, Tamara M., Bonner, James A., Gillespie, G. Yancey, Yang, Eddy S., Willey, Christopher D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756473/
https://ncbi.nlm.nih.gov/pubmed/22619307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3091
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