MARCKS Regulates Growth, Radiation Sensitivity and is a Novel Prognostic Factor for Glioma

PURPOSE: This study assessed whether Myristoylated Alanine Rich C-Kinase Substrate (MARCKS) can regulate glioblastoma (GBM) growth, radiation sensitivity and clinical outcome. EXPERIMENTAL DESIGN: MARCKS protein levels were analyzed in five GBM explant cell lines and eight patient-derived xenograft...

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Hauptverfasser: Jarboe, John S., Anderson, Joshua C., Duarte, Christine W., Mehta, Tapan, Nowsheen, Somaira, Hicks, Patricia H., Whitley, Alexander C., Rohrbach, Timothy D., McCubrey, Raymond O., Chiu, Sherard, Burleson, Tamara M., Bonner, James A., Gillespie, G. Yancey, Yang, Eddy S., Willey, Christopher D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3756473/
https://ncbi.nlm.nih.gov/pubmed/22619307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-3091
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