Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression

Targeting activated fibroblasts, including myofibroblast differentiation, has emerged as a key therapeutic strategy in patients with idiopathic pulmonary fibrosis (IPF). However, there is no available therapy capable of selectively eradicating myofibroblasts or limiting their genesis. Through an int...

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Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Yang, David C., Li, Ji-Min, Xu, Jihao, Oldham, Justin, Phan, Sem H., Last, Jerold A., Wu, Reen, Chen, Ching-Hsien
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6894092/
https://ncbi.nlm.nih.gov/pubmed/31661644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201901705R
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