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Phase Transitions of Spindle-Associated Protein Regulate Spindle Apparatus Assembly
Spindle assembly required during mitosis depends on microtubule polymerization. We demonstrate that the evolutionarily conserved low-complexity protein, BuGZ, undergoes phase transition or coacervation to promote assembly of both spindles and their associated components. BuGZ forms temperature-depen...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4607269/ https://ncbi.nlm.nih.gov/pubmed/26388440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.010 |
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