Phase Transitions of Spindle-Associated Protein Regulate Spindle Apparatus Assembly

Spindle assembly required during mitosis depends on microtubule polymerization. We demonstrate that the evolutionarily conserved low-complexity protein, BuGZ, undergoes phase transition or coacervation to promote assembly of both spindles and their associated components. BuGZ forms temperature-depen...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cell
Hoofdauteurs: Jiang, Hao, Wang, Shusheng, Huang, Yuejia, He, Xiaonan, Cui, Honggang, Zhu, Xueliang, Zheng, Yixian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607269/
https://ncbi.nlm.nih.gov/pubmed/26388440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.08.010
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items