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Mutation in NRAS in familial Noonan syndrome – case report and review of the literature

BACKGROUND: Noonan syndrome (NS), a heterogeneous developmental disorder associated with variable clinical expression including short stature, congenital heart defect, unusual pectus deformity and typical facial features, is caused by activating mutations in genes involved in the RAS-MAPK signaling...

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Bibliografische gegevens
Gepubliceerd in:BMC Med Genet
Hoofdauteurs: Ekvall, Sara, Wilbe, Maria, Dahlgren, Jovanna, Legius, Eric, van Haeringen, Arie, Westphal, Otto, Annerén, Göran, Bondeson, Marie-Louise
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607013/
https://ncbi.nlm.nih.gov/pubmed/26467218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0239-1
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