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Mutation in NRAS in familial Noonan syndrome – case report and review of the literature

BACKGROUND: Noonan syndrome (NS), a heterogeneous developmental disorder associated with variable clinical expression including short stature, congenital heart defect, unusual pectus deformity and typical facial features, is caused by activating mutations in genes involved in the RAS-MAPK signaling...

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Bibliografiske detaljer
Udgivet i:BMC Med Genet
Main Authors: Ekvall, Sara, Wilbe, Maria, Dahlgren, Jovanna, Legius, Eric, van Haeringen, Arie, Westphal, Otto, Annerén, Göran, Bondeson, Marie-Louise
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4607013/
https://ncbi.nlm.nih.gov/pubmed/26467218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0239-1
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